Morrison1989 - Folate Cycle Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_dihydrofolate_free",
        "label": "Dihydrofolate free",
        "units": "native SBML value",
        "default": 0.0012,
        "maps_to": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.initial_dihydrofolate_free",
        "description": "Initial Dihydrofolate free. Sets the initial value of bundled SBML symbol `FH2f`."
      },
      {
        "name": "initial_tetrahydrofolate",
        "label": "Tetrahydrofolate",
        "units": "native SBML value",
        "default": 0.46,
        "maps_to": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.initial_tetrahydrofolate",
        "description": "Initial Tetrahydrofolate. Sets the initial value of bundled SBML symbol `FH4`."
      },
      {
        "name": "initial_dihydrofolate_reductase_free",
        "label": "Dihydrofolate reductase free",
        "units": "native SBML value",
        "default": 0.64,
        "maps_to": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.initial_dihydrofolate_reductase_free",
        "description": "Initial Dihydrofolate reductase free. Sets the initial value of bundled SBML symbol `DHFRf`."
      }
    ],
    "outputs": [
      {
        "name": "dihydrofolate_free",
        "maps_to": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.dihydrofolate_free",
        "description": "Dihydrofolate free observable. Maps to SBML symbol `FH2f`."
      },
      {
        "name": "tetrahydrofolate",
        "maps_to": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.tetrahydrofolate",
        "description": "Tetrahydrofolate observable. Maps to SBML symbol `FH4`."
      },
      {
        "name": "10_formyl_dihydrofolate",
        "maps_to": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.10_formyl_dihydrofolate",
        "description": "10 formyl dihydrofolate observable. Maps to SBML symbol `FFH2`."
      },
      {
        "name": "dihydrofolate_reductase_free",
        "maps_to": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.dihydrofolate_reductase_free",
        "description": "Dihydrofolate reductase free observable. Maps to SBML symbol `DHFRf`."
      },
      {
        "name": "5_10_methylene_tetrahydrofolate",
        "maps_to": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.5_10_methylene_tetrahydrofolate",
        "description": "5,10 methylene tetrahydrofolate observable. Maps to SBML symbol `CH2FH4`."
      },
      {
        "name": "5_methyl_tetrahydrofolate",
        "maps_to": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.5_methyl_tetrahydrofolate",
        "description": "5 methyl tetrahydrofolate observable. Maps to SBML symbol `CH3FH4`."
      },
      {
        "name": "state",
        "maps_to": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.state",
        "description": "Full raw SBML observable record for reproducibility and downstream visualisation."
      },
      {
        "name": "summary",
        "maps_to": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.summary",
        "description": "Change and peak summary across the simulated SBML observables."
      },
      {
        "name": "species_labels",
        "maps_to": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.species_labels",
        "description": "Mapping from selected raw SBML observable symbols to display labels."
      }
    ]
  },
  "tags": [
    "biomodels_ebi",
    "curated",
    "faithful",
    "metabolism",
    "oncology",
    "physiology",
    "sbml",
    "systemsbiology",
    "tumor-growth"
  ],
  "title": "Morrison1989 - Folate Cycle Lab",
  "models": [
    {
      "path": "owned/models/oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model",
      "alias": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model",
      "provenance": {
        "owned_path": "owned/models/oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model_state"
      ],
      "from": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.state"
    },
    {
      "to": [
        "visualisation.oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model_summary"
      ],
      "from": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.summary"
    },
    {
      "to": [
        "visualisation.oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model_species_labels"
      ],
      "from": "oncology_sbml_morrison1989_folate_cycle_biomd0000000018_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "Morrison1989 - Folate Cycle The model describes the folate cyclekinetics in breast cancer cells. This model is described in the article: Folate cycle kinetics in human breast cancer cells.",
  "schema_version": "2.0"
}