Tiago2010_FeMetabolism_FeLoaded Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_iron_in_plasma",
        "units": "native SBML value",
        "default": 100,
        "maps_to": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.initial_iron_in_plasma",
        "description": "Initial condition for iron in plasma. Maps to bundled SBML symbol `s1`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_iron_in_bone_marrow",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.initial_iron_in_bone_marrow",
        "description": "Initial condition for iron in bone marrow. Maps to bundled SBML symbol `s2`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_iron_metabolism_state_3",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.initial_iron_metabolism_state_3",
        "description": "Initial condition for iron metabolism state 3. Maps to bundled SBML symbol `s3`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_iron_in_spleen",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.initial_iron_in_spleen",
        "description": "Initial condition for iron in spleen. Maps to bundled SBML symbol `s4`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_iron_in_liver",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.initial_iron_in_liver",
        "description": "Initial condition for iron in liver. Maps to bundled SBML symbol `s5`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      }
    ],
    "outputs": [
      {
        "name": "iron_in_plasma",
        "maps_to": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.iron_in_plasma"
      },
      {
        "name": "iron_in_bone_marrow",
        "maps_to": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.iron_in_bone_marrow"
      },
      {
        "name": "iron_metabolism_state_3",
        "maps_to": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.iron_metabolism_state_3"
      },
      {
        "name": "iron_in_spleen",
        "maps_to": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.iron_in_spleen"
      },
      {
        "name": "iron_in_liver",
        "maps_to": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.iron_in_liver"
      },
      {
        "name": "observable_values",
        "maps_to": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.observable_values"
      },
      {
        "name": "run_summary",
        "maps_to": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.run_summary"
      },
      {
        "name": "observable_labels",
        "maps_to": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.observable_labels"
      }
    ]
  },
  "title": "Tiago2010_FeMetabolism_FeLoaded Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model",
      "parameters": {
        "model_path": "data/BIOMD0000000261.xml",
        "integration_step": 0.1
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model_observable_values"
      ],
      "from": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.observable_values"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model_run_summary"
      ],
      "from": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.run_summary"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model_observable_labels"
      ],
      "from": "metabolism_sbml_tiago2010_femetabolism_feloaded_biomd0000000261_model.observable_labels"
    }
  ],
  "package": "tiago2010-femetabolism-feloaded",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "This a model from the article: Systems analysis of iron metabolism: the network of iron pools and fluxes Tiago JS Lopes, Tatyana Luganskaja, Maja Vujic-Spasic, Matthias W Hentze, Martina U Muckenthale. It can be used to explore metabolic flux dynamics and compare pathway behavior across conditions.",
  "schema_version": "2.0"
}