Bunimovich-Mendrazitsky2007 - Mathematical model of BCG immunotherapy Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_effector_cells",
        "label": "Initial Effector Cells",
        "units": "native source value",
        "default": 0.05,
        "maps_to": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.initial_effector_cells",
        "description": "Initial Effector Cells. Sets the initial value of bundled SBML species `Effector_cells`."
      },
      {
        "name": "initial_tumor_infected_cells",
        "label": "Initial Tumor Infected Cells",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.initial_tumor_infected_cells",
        "description": "Initial Tumor Infected Cells. Sets the initial value of bundled SBML species `Tumor_infected_cells`."
      },
      {
        "name": "initial_tumor_uninfected_cells",
        "label": "Initial Tumor Uninfected Cells",
        "units": "native source value",
        "default": 0.55,
        "maps_to": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.initial_tumor_uninfected_cells",
        "description": "Initial Tumor Uninfected Cells. Sets the initial value of bundled SBML species `Tumor_uninfected_cells`."
      },
      {
        "name": "initial_bcg",
        "label": "Initial BCG",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.initial_bcg",
        "description": "Initial BCG. Sets the initial value of bundled SBML species `BCG`."
      },
      {
        "name": "tumor_growth_rate",
        "label": "Tumor Growth Rate",
        "units": "native source value",
        "default": 0.0155,
        "maps_to": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.tumor_growth_rate",
        "description": "Tumor Growth Rate. Sets bundled SBML parameter `beta`."
      },
      {
        "name": "tumor_growth_rate_2",
        "label": "Tumor Growth Rate 2",
        "units": "native source value",
        "default": 0.12,
        "maps_to": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.tumor_growth_rate_2",
        "description": "Tumor Growth Rate 2. Sets bundled SBML parameter `r`."
      }
    ],
    "outputs": [
      {
        "name": "effector_cells",
        "maps_to": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.effector_cells"
      },
      {
        "name": "tumor_infected_cells",
        "maps_to": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.tumor_infected_cells"
      },
      {
        "name": "tumor_uninfected_cells",
        "maps_to": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.tumor_uninfected_cells"
      },
      {
        "name": "bcg",
        "maps_to": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.bcg"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.species_labels"
      }
    ]
  },
  "title": "Bunimovich-Mendrazitsky2007 - Mathematical model of BCG immunotherapy Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model",
      "alias": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model_state"
      ],
      "from": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model_summary"
      ],
      "from": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model_species_labels"
      ],
      "from": "immunology_sbml_bunimovich_mendrazitsky2007_mathematical_model_o_biomd0000001034_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "This ordinary differential equation model, simulating the tumor-immune interactions involved in BCG immunotherapy to treat superficial bladder cancer, is described by the publication:Bunimovich-Mendra. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}