Smith2013 - Regulation of Insulin Signalling by Oxidative Stress Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_cytoplasm_foxo1_tot",
        "label": "Initial Cytoplasm Foxo1 Tot",
        "maps_to": "signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model.initial_cytoplasm_foxo1_tot",
        "description": "Initial level of Cytoplasm Foxo1 Tot. Maps to SBML symbol `cytoplasm_Foxo1_tot`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_dnabound_foxo1_tot",
        "label": "Initial Dnabound Foxo1 Tot",
        "maps_to": "signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model.initial_dnabound_foxo1_tot",
        "description": "Initial level of Dnabound Foxo1 Tot. Maps to SBML symbol `dnabound_Foxo1_tot`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_dusp_dusp_ox",
        "label": "Initial DUSP DUSP Ox",
        "maps_to": "signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model.initial_dusp_dusp_ox",
        "description": "Initial level of DUSP DUSP Ox. Maps to SBML symbol `DUSP_plus_DUSP_ox`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "in_r_active",
        "label": "In R active",
        "maps_to": "signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model.in_r_active",
        "description": "In R active. Maps to SBML symbol `InR_active` and is emitted in native SBML units."
      },
      {
        "name": "akt",
        "label": "AKT",
        "maps_to": "signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model.akt",
        "description": "AKT. Maps to SBML symbol `Akt` and is emitted in native SBML units."
      },
      {
        "name": "source_defined_akt_p2_state",
        "label": "source-defined AKT_P2 state",
        "maps_to": "signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model.source_defined_akt_p2_state",
        "description": "source-defined AKT_P2 state. Maps to SBML symbol `Akt_P2` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "stress-response",
    "metabolic-signaling",
    "hormone-signaling"
  ],
  "title": "Smith2013 - Regulation of Insulin Signalling by Oxidative Stress Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model_state"
      ],
      "from": "signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model_summary"
      ],
      "from": "signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model_species_labels"
      ],
      "from": "signaling_sbml_smith2013_regulation_of_insulin_signalling_by_ox_biomd0000000474_model.species_labels"
    }
  ],
  "package": "smith2013-regulation-of-insulin-signalling-by-ox",
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "version": "1.0.0",
  "description": "Clean Biosimulant lab for metabolic and hormone-linked signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}