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Lai2014 Hemiconcerted Mwc Model Of Intact Calmodulin With Two Targ Lab

About lab

Lai2014 - Hemiconcerted MWC model of intactcalmodulin with two targets This model is described in the article: Modulation of calmodulin lobes by different targets: an allosteric model with hemiconcert. It can be used to explore systemsbiology lai2014 hemiconcerted mwc of intact dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
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Metadata

Packagelai2014-hemiconcerted-mwc-model-of-intact-calmodulin-with-two-ta
Created2026-05-17
Updated2026-05-17
metabolismsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_model_state_rbp",
        "label": "Initial Model State Rbp",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.initial_model_state_rbp",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `rbp`."
      },
      {
        "name": "initial_cam_tt_0_0",
        "label": "Initial Cam Tt 0 0",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.initial_cam_tt_0_0",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `cam_TT_0_0`."
      },
      {
        "name": "initial_model_state_tbp",
        "label": "Initial Model State Tbp",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.initial_model_state_tbp",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `tbp`."
      },
      {
        "name": "initial_cam_tt_d_tbp",
        "label": "Initial Cam Tt D Tbp",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.initial_cam_tt_d_tbp",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `cam_TT_D_tbp`."
      },
      {
        "name": "initial_cam_tt_d_rbp",
        "label": "Initial Cam Tt D Rbp",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.initial_cam_tt_d_rbp",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `cam_TT_D_rbp`."
      },
      {
        "name": "initial_cam_tt_d_0",
        "label": "Initial Cam Tt D 0",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.initial_cam_tt_d_0",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `cam_TT_D_0`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.species_labels"
      },
      {
        "name": "rbp",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.rbp"
      },
      {
        "name": "cam_tt_0_0",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.cam_tt_0_0"
      },
      {
        "name": "tbp",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.tbp"
      },
      {
        "name": "cam_tt_d_tbp",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.cam_tt_d_tbp"
      },
      {
        "name": "cam_tt_d_rbp",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.cam_tt_d_rbp"
      },
      {
        "name": "cam_tt_d_0",
        "maps_to": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.cam_tt_d_0"
      }
    ]
  },
  "tags": [
    "metabolism",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Lai2014 Hemiconcerted Mwc Model Of Intact Calmodulin With Two Targ Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model",
      "alias": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model_state"
      ],
      "from": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model_summary"
      ],
      "from": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model_species_labels"
      ],
      "from": "systemsbiology_sbml_lai2014_hemiconcerted_mwc_model_of_intact_calmod_biomd0000000574_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Lai2014 - Hemiconcerted MWC model of intactcalmodulin with two targets This model is described in the article: Modulation of calmodulin lobes by different targets: an allosteric model with hemiconcert. It can be used to explore systemsbiology lai2014 hemiconcerted mwc of intact dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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