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Orfeo2010 Simulating The Effects Of Fondaparinux And Rivaroxaban On Lab

About lab

Reused mathematical model (Hockin et al., 2002) of blood coagulation simulating the effects of coagulation factor inhibitors, fondaparinux (synthetic heparin) and Rivaroxaban. It can be used to explore systemsbiology orfeo2010 simulating the effects of dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packageorfeo2010-simulating-the-effects-of-fondaparinux-and-rivaroxaban
Created2026-05-17
Updated2026-05-17
generegulationpharmacologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_m_i_ia_atiii",
        "label": "Initial M I Ia Atiii",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.initial_m_i_ia_atiii",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `mIIa_ATIII`."
      },
      {
        "name": "initial_m_i_ia",
        "label": "Initial M I Ia",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.initial_m_i_ia",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `mIIa`."
      },
      {
        "name": "initial_xa_va_ii",
        "label": "Initial Xa Va Ii",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.initial_xa_va_ii",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Xa_Va_II`."
      },
      {
        "name": "initial_xa_va",
        "label": "Initial Xa Va",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.initial_xa_va",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Xa_Va`."
      },
      {
        "name": "initial_xa_tfpi",
        "label": "Initial Xa Tfpi",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.initial_xa_tfpi",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Xa_TFPI`."
      },
      {
        "name": "initial_xa_atiii",
        "label": "Initial Xa Atiii",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.initial_xa_atiii",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Xa_ATIII`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.species_labels"
      },
      {
        "name": "m_i_ia_atiii",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.m_i_ia_atiii"
      },
      {
        "name": "m_i_ia",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.m_i_ia"
      },
      {
        "name": "xa_va_ii",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.xa_va_ii"
      },
      {
        "name": "xa_va",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.xa_va"
      },
      {
        "name": "xa_tfpi",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.xa_tfpi"
      },
      {
        "name": "xa_atiii",
        "maps_to": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.xa_atiii"
      }
    ]
  },
  "tags": [
    "generegulation",
    "pharmacology",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Orfeo2010 Simulating The Effects Of Fondaparinux And Rivaroxaban On Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model",
      "alias": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model_state"
      ],
      "from": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model_summary"
      ],
      "from": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model_species_labels"
      ],
      "from": "systemsbiology_sbml_orfeo2010_simulating_the_effects_of_fondaparinux_model1807240001_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Reused mathematical model (Hockin et al., 2002) of blood coagulation simulating the effects of coagulation factor inhibitors, fondaparinux (synthetic heparin) and Rivaroxaban. It can be used to explore systemsbiology orfeo2010 simulating the effects of dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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