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Kogan2013 A Mathematical Model For The Immunotherapeutic Control Of Lab

About lab

This is a mathematical model describing the imbalance between T helper (Th1/Th2) cell types in melanome patients, together with its regulation via IL-12 treatment. It can be used to explore systemsbiology kogan2013 a mathematical for the dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packagekogan2013-a-mathematical-model-for-the-immunotherapeutic-control
Created2026-05-17
Updated2026-05-17
oncologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_model_state_t_2",
        "label": "Initial Model State T 2",
        "maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.initial_model_state_t_2",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `T_2`."
      },
      {
        "name": "initial_model_state_t_1",
        "label": "Initial Model State T 1",
        "maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.initial_model_state_t_1",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `T_1`."
      },
      {
        "name": "initial_model_state_i",
        "label": "Initial Model State I",
        "maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.initial_model_state_i",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `I`."
      },
      {
        "name": "initial_model_state_g",
        "label": "Initial Model State G",
        "maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.initial_model_state_g",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `G`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.species_labels"
      },
      {
        "name": "t_2",
        "maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.t_2"
      },
      {
        "name": "t_1",
        "maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.t_1"
      },
      {
        "name": "model_state_i",
        "maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.model_state_i"
      },
      {
        "name": "model_state_g",
        "maps_to": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.model_state_g"
      }
    ]
  },
  "tags": [
    "oncology",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Kogan2013 A Mathematical Model For The Immunotherapeutic Control Of Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model",
      "alias": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model_state"
      ],
      "from": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model_summary"
      ],
      "from": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model_species_labels"
      ],
      "from": "systemsbiology_sbml_kogan2013_a_mathematical_model_for_the_immunothe_biomd0000000881_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "This is a mathematical model describing the imbalance between T helper (Th1/Th2) cell types in melanome patients, together with its regulation via IL-12 treatment. It can be used to explore systemsbiology kogan2013 a mathematical for the dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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