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Banerjee2015 - A Mathematical Model to Elucidate BrainTumor Abrogation by Immunotherapywith T11 Target Structure Lab

About lab

T11 Target structure (T11TS), a membrane glycoprotein isolated from sheep erythrocytes, reverses the immune suppressed state of brain tumor induced animals by boosting the functional status of the imm. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packagebanerjee2015-a-mathematical-model-to-elucidate-braintumor-abroga
Created2026-05-15
Updated2026-05-15
immunologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_unresolved_tumor_observable_1",
        "label": "Initial Unresolved Tumor Observable 1",
        "units": "native source value",
        "default": 857419,
        "maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.initial_unresolved_tumor_observable_1",
        "description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `G`."
      },
      {
        "name": "initial_unresolved_tumor_observable_2",
        "label": "Initial Unresolved Tumor Observable 2",
        "units": "native source value",
        "default": 943092,
        "maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.initial_unresolved_tumor_observable_2",
        "description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `M`."
      },
      {
        "name": "initial_unresolved_tumor_observable_3",
        "label": "Initial Unresolved Tumor Observable 3",
        "units": "native source value",
        "default": 303.397,
        "maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.initial_unresolved_tumor_observable_3",
        "description": "Initial Unresolved Tumor Observable 3. Sets the initial value of bundled SBML species `CT`."
      },
      {
        "name": "initial_unresolved_tumor_observable_4",
        "label": "Initial Unresolved Tumor Observable 4",
        "units": "native source value",
        "default": 9134.33,
        "maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.initial_unresolved_tumor_observable_4",
        "description": "Initial Unresolved Tumor Observable 4. Sets the initial value of bundled SBML species `TB`."
      },
      {
        "name": "initial_unresolved_tumor_observable_5",
        "label": "Initial Unresolved Tumor Observable 5",
        "units": "native source value",
        "default": 0.303397,
        "maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.initial_unresolved_tumor_observable_5",
        "description": "Initial Unresolved Tumor Observable 5. Sets the initial value of bundled SBML species `IG`."
      },
      {
        "name": "cytokine_transforming_growth_factor_beta_removal_rate",
        "label": "Cytokine Transforming Growth Factor Beta Removal Rate",
        "units": "native source value",
        "default": 6.93,
        "maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.cytokine_transforming_growth_factor_beta_removal_rate",
        "description": "Cytokine Transforming Growth Factor Beta Removal Rate. Sets bundled SBML parameter `mu_2`."
      }
    ],
    "outputs": [
      {
        "name": "unresolved_tumor_observable_1",
        "maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.unresolved_tumor_observable_1"
      },
      {
        "name": "unresolved_tumor_observable_2",
        "maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.unresolved_tumor_observable_2"
      },
      {
        "name": "unresolved_tumor_observable_3",
        "maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.unresolved_tumor_observable_3"
      },
      {
        "name": "unresolved_tumor_observable_4",
        "maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.unresolved_tumor_observable_4"
      },
      {
        "name": "unresolved_tumor_observable_5",
        "maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.unresolved_tumor_observable_5"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.species_labels"
      }
    ]
  },
  "title": "Banerjee2015 - A Mathematical Model to Elucidate BrainTumor Abrogation by Immunotherapywith T11 Target Structure Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model",
      "alias": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model_state"
      ],
      "from": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model_summary"
      ],
      "from": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model_species_labels"
      ],
      "from": "immunology_sbml_banerjee2015_a_mathematical_model_to_elucidate_b_model1912090003_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "T11 Target structure (T11TS), a membrane glycoprotein isolated from sheep erythrocytes, reverses the immune suppressed state of brain tumor induced animals by boosting the functional status of the imm. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}

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