Bhalla2002_mkp1_feedback_effects Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_dag",
        "label": "Initial DAG",
        "maps_to": "signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model.initial_dag",
        "description": "Initial level of DAG. Maps to SBML symbol `DAG`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_mapk_nucleotides",
        "label": "Initial MAPK Nucleotides",
        "maps_to": "signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model.initial_mapk_nucleotides",
        "description": "Initial level of MAPK Nucleotides. Maps to SBML symbol `MAPK_slash_Nucleotides`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_mapk_ubiquitination",
        "label": "Initial MAPK Ubiquitination",
        "maps_to": "signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model.initial_mapk_ubiquitination",
        "description": "Initial level of MAPK Ubiquitination. Maps to SBML symbol `MAPK_slash_Ubiquitination`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "shc_adapter_protein_adapter_protein_adapter_protein_adapter_protein_adapter_protein_adapter_protein_adapter_protein_active_dot_sos_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_dot_grb2_adapter_protein_adapter_protein_adapter_protein_adapter_protein_adapter_protein_adapter_protein_adapter_protein_sos_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_dot_ras_gef_sos_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_dot_ras_gef_cplx",
        "label": "Shc adapter protein Adapter Protein Adapter Protein Adapter Protein Adapter Protein Adapter Protein Adapter Protein active Dot SOS guanine-nucleotide exchange factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Dot Grb2 adapter protein Adapter Protein Adapter Protein Adapter Protein Adapter Protein Adapter Protein Adapter Protein SOS guanine-nucleotide exchange factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Dot RAS GEF SOS guanine-nucleotide exchange factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Dot RAS GEF Cplx",
        "maps_to": "signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model.shc_adapter_protein_adapter_protein_adapter_protein_adapter_protein_adapter_protein_adapter_protein_adapter_protein_active_dot_sos_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_dot_grb2_adapter_protein_adapter_protein_adapter_protein_adapter_protein_adapter_protein_adapter_protein_adapter_protein_sos_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_dot_ras_gef_sos_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_guanine_nucleotide_exchange_factor_dot_ras_gef_cplx",
        "description": "Shc adapter protein Adapter Protein Adapter Protein Adapter Protein Adapter Protein Adapter Protein Adapter Protein active Dot SOS guanine-nucleotide exchange factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Dot Grb2 adapter protein Adapter Protein Adapter Protein Adapter Protein Adapter Protein Adapter Protein Adapter Protein SOS guanine-nucleotide exchange factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Dot RAS GEF SOS guanine-nucleotide exchange factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Guanine Nucleotide Exchange Factor Dot RAS GEF Cplx. Maps to SBML symbol `Shc_star__dot_Sos_dot_Grb2_slash_Sos_dot_Ras_GEF_slash_Sos_dot_Ras_GEF_cplx` and is emitted in native SBML units."
      },
      {
        "name": "calcium_bound_pkc",
        "label": "Calcium bound PKC",
        "maps_to": "signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model.calcium_bound_pkc",
        "description": "Calcium bound PKC. Maps to SBML symbol `PKC_slash_PKC_minus_Ca` and is emitted in native SBML units."
      },
      {
        "name": "arachidonic_acid_active_calcium_bound_pkc",
        "label": "Arachidonic Acid active Calcium bound PKC",
        "maps_to": "signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model.arachidonic_acid_active_calcium_bound_pkc",
        "description": "Arachidonic Acid active Calcium bound PKC. Maps to SBML symbol `PKC_slash_PKC_minus_Ca_minus_AA_star_` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "mapk",
    "neuroscience"
  ],
  "title": "Bhalla2002_mkp1_feedback_effects Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model_state"
      ],
      "from": "signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model_summary"
      ],
      "from": "signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model_species_labels"
      ],
      "from": "signaling_sbml_bhalla2002_mkp1_feedback_effects_model9070467164_model.species_labels"
    }
  ],
  "package": "bhalla2002-mkp1-feedback-effects",
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "version": "1.0.0",
  "description": "Clean Biosimulant lab for MAPK/ERK receptor signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}