About lab
Proctor2017- Role of microRNAs in osteoarthritis (miR140 in osteoarthritis) This model is described in the article: Computer simulation models as a tool to investigate the role of microRNAs in osteoar. It can be used to explore systemsbiology proctor2017 role of micrornas in dynamics and compare simulation behavior across conditions.
Runtime
Duration1
Comms Step0.1
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Metadata
Packageproctor2017-role-of-micrornas-in-osteoarthritis-7-lab
Created2026-05-17
Updated2026-05-17
generegulationsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation
Manifest
{
"io": {
"inputs": [
{
"name": "initial_tn_fa",
"label": "Initial Tn Fa",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.initial_tn_fa",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `TNFa`."
},
{
"name": "initial_tg_fb_a",
"label": "Initial Tg Fb A",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.initial_tg_fb_a",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `TGFb_A`."
},
{
"name": "initial_ik_b_n_fk_b",
"label": "Initial Ik B N Fk B",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.initial_ik_b_n_fk_b",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `IkB_NFkB`."
},
{
"name": "initial_n_fk_b",
"label": "Initial N Fk B",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.initial_n_fk_b",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `NFkB`."
},
{
"name": "initial_tg_fb_i",
"label": "Initial Tg Fb I",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.initial_tg_fb_i",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `TGFb_I`."
},
{
"name": "initial_mi_r140_gene_n_fk_b",
"label": "Initial Mi R140 Gene N Fk B",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.initial_mi_r140_gene_n_fk_b",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `miR140_gene_NFkB`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.species_labels"
},
{
"name": "tn_fa",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.tn_fa"
},
{
"name": "tg_fb_a",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.tg_fb_a"
},
{
"name": "ik_b_n_fk_b",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.ik_b_n_fk_b"
},
{
"name": "n_fk_b",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.n_fk_b"
},
{
"name": "tg_fb_i",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.tg_fb_i"
},
{
"name": "mi_r140_gene_n_fk_b",
"maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.mi_r140_gene_n_fk_b"
}
]
},
"tags": [
"generegulation",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Proctor2017 Role Of Micrornas In Osteoarthritis 7 Lab",
"models": [
{
"path": "owned/models/systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model",
"alias": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model",
"provenance": {
"owned_path": "owned/models/systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model"
}
},
{
"path": "owned/models/visualisation",
"alias": "visualisation",
"provenance": {
"owned_path": "owned/models/visualisation"
}
}
],
"wiring": [
{
"to": [
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],
"from": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.state"
},
{
"to": [
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],
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},
{
"to": [
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],
"from": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170005_model.species_labels"
}
],
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"description": "Proctor2017- Role of microRNAs in osteoarthritis (miR140 in osteoarthritis) This model is described in the article: Computer simulation models as a tool to investigate the role of microRNAs in osteoar. It can be used to explore systemsbiology proctor2017 role of micrornas in dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
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