About lab
Holmes2006 Hill S Model Of Muscle Contraction
This Biosimulant lab wraps Holmes2006 Hill S Model Of Muscle Contraction as a runnable systems biology model with a companion visualization module.
Holmes2006 - Hill's model of muscle contraction This model is described in the article: Teaching from classic papers: Hill's model of muscle contraction. It can be used to explore the configured dynamics and compare scenario outcomes across configurations.
What You'll See
The lab asks: Which physiological state variables carry the strongest baseline response? Source model: Holmes2006 - Hill's model of muscle contraction. It runs for 1.0 time units with a communication step of 0.1. The run uses the model defaults declared by the curated SBML wrapper. The generated visualizations focus on L Ce, combining trajectory, endpoint-comparison, and summary-table views from one completed dark-mode run.
In this captured run, L Ce moved from 0.7000 to 0.6046 across 1.0 simulation windows.
Output Visualizations
Summary table for Holmes2006 Hill S Model Of Muscle Contraction, reporting the scientific question, observed answer, dominant module, and caveat.
Trajectories of L Ce across the 1.0 simulation. In this run L Ce fell from 0.7000 to 0.6046 — the largest movements among the focused observables.
Largest-excursion ranking of the focused observables — the absolute movement magnitude during the run. Top 1: L Ce = 0.0954.
Endpoint snapshot of the focused observables — final values from the captured run. Top 1 by value: L Ce = 0.6046.
Model Context
- Core model:
models/core - Visualization model:
models/visualisation - Standard:
other - Upstream source:
biomodels_ebi:BIOMD0000000677 - License:
CC0
Inputs
| Input | Maps To | Default | Notes |
|---|---|---|---|
| Initial L Ce | systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model.initial_l_ce | Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol L_ce. |
Outputs
| Output | Maps To | Role |
|---|---|---|
state | systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model.state | Available to the visualization model and downstream workflows. |
summary | systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model.summary | Available to the visualization model and downstream workflows. |
species_labels | systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model.species_labels | Available to the visualization model and downstream workflows. |
l_ce | systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model.l_ce | Available to the visualization model and downstream workflows. |
Runtime
- Duration:
1.0 - Communication step:
0.1
Running Locally
biosimulant labs serve
Holmes2006 - Hill's model of muscle contraction This model is described in the article: Teaching from classic papers: Hill's model of muscle contraction. It can be used to explore systemsbiology holmes2006 hill s of muscle dynamics and compare simulation behavior across conditions.
Runtime
Runs
Metadata
Manifest
{
"io": {
"inputs": [
{
"name": "initial_l_ce",
"label": "Initial L Ce",
"maps_to": "systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model.initial_l_ce",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `L_ce`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model.species_labels"
},
{
"name": "l_ce",
"maps_to": "systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model.l_ce"
}
]
},
"tags": [
"physiology",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Holmes2006 Hill S Model Of Muscle Contraction Lab",
"models": [
{
"path": "owned/models/systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model",
"alias": "systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model",
"provenance": {
"owned_path": "owned/models/systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model"
}
},
{
"path": "owned/models/visualisation",
"alias": "visualisation",
"provenance": {
"owned_path": "owned/models/visualisation"
}
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model_state"
],
"from": "systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model_summary"
],
"from": "systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model_species_labels"
],
"from": "systemsbiology_sbml_holmes2006_hill_s_model_of_muscle_contraction_biomd0000000677_model.species_labels"
}
],
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"description": "Holmes2006 - Hill's model of muscle contraction This model is described in the article: Teaching from classic papers: Hill's model of muscle contraction. It can be used to explore systemsbiology holmes2006 hill s of muscle dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
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