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Steckmann2012 Amyloid Beta Protein Fibrillogenesis Lab

About lab

Steckmann2012 - Amyloid beta-proteinfibrillogenesis (kinetics of secondary structure conversion) This model is described in the article: Kinetics of peptide secondary structure conversion during amylo. It can be used to explore systemsbiology steckmann2012 amyloid beta protein fibrillogenes dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packagesteckmann2012-amyloid-beta-protein-fibrillogenesis-lab
Created2026-05-17
Updated2026-05-17
generegulationsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_beta",
        "label": "Initial Beta",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.initial_beta",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `beta`."
      },
      {
        "name": "initial_alpha",
        "label": "Initial Alpha",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.initial_alpha",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `alpha`."
      },
      {
        "name": "initial_rct0",
        "label": "Initial Rct0",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.initial_rct0",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `RCT0`."
      },
      {
        "name": "initial_model_state_rc",
        "label": "Initial Model State Rc",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.initial_model_state_rc",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `RC`."
      },
      {
        "name": "initial_model_state_bn1",
        "label": "Initial Model State BN1",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.initial_model_state_bn1",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `BN1`."
      },
      {
        "name": "initial_rct1",
        "label": "Initial Rct1",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.initial_rct1",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `RCT1`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.species_labels"
      },
      {
        "name": "beta",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.beta"
      },
      {
        "name": "alpha",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.alpha"
      },
      {
        "name": "rct0",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.rct0"
      },
      {
        "name": "model_state_rc",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.model_state_rc"
      },
      {
        "name": "bn1",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.bn1"
      },
      {
        "name": "rct1",
        "maps_to": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.rct1"
      }
    ]
  },
  "tags": [
    "generegulation",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Steckmann2012 Amyloid Beta Protein Fibrillogenesis Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model",
      "alias": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model_state"
      ],
      "from": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model_summary"
      ],
      "from": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model_species_labels"
      ],
      "from": "systemsbiology_sbml_steckmann2012_amyloid_beta_protein_fibrillogenes_biomd0000000533_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Steckmann2012 - Amyloid beta-proteinfibrillogenesis (kinetics of secondary structure conversion) This model is described in the article: Kinetics of peptide secondary structure conversion during amylo. It can be used to explore systemsbiology steckmann2012 amyloid beta protein fibrillogenes dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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