Ito2019 - gefitnib resistance of lung adenocarcinoma caused by MET amplification Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_x_1_egfr",
        "label": "Initial X 1 EGFR",
        "maps_to": "signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model.initial_x_1_egfr",
        "description": "Initial level of X 1 EGFR. Maps to SBML symbol `X_1_EGFR`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_x_4_egfr_egfr",
        "label": "Initial X 4 EGFR EGFR",
        "maps_to": "signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model.initial_x_4_egfr_egfr",
        "description": "Initial level of X 4 EGFR EGFR. Maps to SBML symbol `X_4_EGFR_EGFR`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_x_5_egfr_erb_b3",
        "label": "Initial X 5 EGFR Erb B3",
        "maps_to": "signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model.initial_x_5_egfr_erb_b3",
        "description": "Initial level of X 5 EGFR Erb B3. Maps to SBML symbol `X_5_EGFR_ErbB3`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "x_1_egfr",
        "label": "X 1 EGFR",
        "maps_to": "signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model.x_1_egfr",
        "description": "X 1 EGFR. Maps to SBML symbol `X_1_EGFR` and is emitted in native SBML units."
      },
      {
        "name": "x_4_egfr_egfr",
        "label": "X 4 EGFR EGFR",
        "maps_to": "signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model.x_4_egfr_egfr",
        "description": "X 4 EGFR EGFR. Maps to SBML symbol `X_4_EGFR_EGFR` and is emitted in native SBML units."
      },
      {
        "name": "x_2_erb_b3",
        "label": "X 2 Erb B3",
        "maps_to": "signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model.x_2_erb_b3",
        "description": "X 2 Erb B3. Maps to SBML symbol `X_2_ErbB3` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "oncology",
    "pharmacology"
  ],
  "title": "Ito2019 - gefitnib resistance of lung adenocarcinoma caused by MET amplification Lab",
  "models": [
    {
      "path": "owned/models/signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model",
      "alias": "signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model",
      "provenance": {
        "owned_path": "owned/models/signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model_state"
      ],
      "from": "signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model_summary"
      ],
      "from": "signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model_species_labels"
      ],
      "from": "signaling_sbml_ito2019_gefitnib_resistance_of_lung_adenocarcino_biomd0000000827_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Clean Biosimulant lab for systems signaling model: Ito2019 - gefitnib resistance of lung adenocarcinoma caused by MET amplification. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}