About lab
This is the first report evaluating the use of fluorescent imaging to determine the pharmacokinetics, lymphatic uptake, and bioavailability of a near-infrared dye-labeled antibody conjugate. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.
Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packagewu2017-murine-bevacizumab-pk-model-lab
Created2026-05-15
Updated2026-05-15
immunologysbmlbiomodels_ebifaithfulcuratedvisualisation
Manifest
{
"io": {
"inputs": [
{
"name": "dose_iv_parameter",
"label": "Dose Iv Parameter",
"units": "native source value",
"default": 0.45,
"maps_to": "immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model.dose_iv_parameter",
"description": "Dose Iv Parameter. Sets bundled SBML parameter `dose_iv`."
},
{
"name": "dose_sc_parameter",
"label": "Dose Sc Parameter",
"units": "native source value",
"default": 0.45,
"maps_to": "immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model.dose_sc_parameter",
"description": "Dose Sc Parameter. Sets bundled SBML parameter `dose_sc`."
}
],
"outputs": [
{
"name": "cs_iv",
"maps_to": "immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model.cs_iv"
},
{
"name": "at_iv",
"maps_to": "immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model.at_iv"
},
{
"name": "cs_sc",
"maps_to": "immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model.cs_sc"
},
{
"name": "at_sc",
"maps_to": "immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model.at_sc"
},
{
"name": "cln_sc",
"maps_to": "immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model.cln_sc"
},
{
"name": "state",
"maps_to": "immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model.species_labels"
}
]
},
"title": "Wu2017 - Murine Bevacizumab PK model Lab",
"models": [
{
"path": "owned/models/immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model",
"alias": "immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model",
"provenance": {
"owned_path": "owned/models/immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model"
}
},
{
"path": "owned/models/visualisation",
"alias": "visualisation",
"provenance": {
"owned_path": "owned/models/visualisation"
}
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model_state"
],
"from": "immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model.state"
},
{
"to": [
"visualisation.immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model_summary"
],
"from": "immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model_species_labels"
],
"from": "immunology_sbml_wu2017_murine_bevacizumab_pk_model_model2003030003_model.species_labels"
}
],
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"description": "This is the first report evaluating the use of fluorescent imaging to determine the pharmacokinetics, lymphatic uptake, and bioavailability of a near-infrared dye-labeled antibody conjugate. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
"schema_version": "2.0"
}Sign in to start your own run. Public-lab history stays visible here.
Select a run from History to view its results.