Al-Tuwairqi2020 - Dynamics of cancer virotherapy with immune response Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_uninfected_cancer_cells",
        "label": "Initial Uninfected Cancer Cells",
        "units": "native source value",
        "default": 0.5,
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.initial_uninfected_cancer_cells",
        "description": "Initial Uninfected Cancer Cells. Sets the initial value of bundled SBML species `uninfected_cancer_cells`."
      },
      {
        "name": "initial_infected_cancer_cells",
        "label": "Initial Infected Cancer Cells",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.initial_infected_cancer_cells",
        "description": "Initial Infected Cancer Cells. Sets the initial value of bundled SBML species `infected_cancer_cells`."
      },
      {
        "name": "initial_free_virus",
        "label": "Initial Free Virus",
        "units": "native source value",
        "default": 0.01,
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.initial_free_virus",
        "description": "Initial Free Virus. Sets the initial value of bundled SBML species `free_virus`."
      },
      {
        "name": "initial_immune_cells",
        "label": "Initial Immune Cells",
        "units": "native source value",
        "default": 0.01,
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.initial_immune_cells",
        "description": "Initial Immune Cells. Sets the initial value of bundled SBML species `immune_cells`."
      },
      {
        "name": "tumor_growth_rate",
        "label": "Tumor Growth Rate",
        "units": "native source value",
        "default": 0.36,
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.tumor_growth_rate",
        "description": "Tumor Growth Rate. Sets bundled SBML parameter `r_1`."
      },
      {
        "name": "cancer_cell_infection_rate",
        "label": "Cancer Cell Infection Rate",
        "units": "native source value",
        "default": 0.5,
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.cancer_cell_infection_rate",
        "description": "Cancer Cell Infection Rate. Sets bundled SBML parameter `a`."
      },
      {
        "name": "uninfected_cancer_cell_killing_death_rate",
        "label": "Uninfected Cancer Cell Killing Death Rate",
        "units": "native source value",
        "default": 0.1278,
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.uninfected_cancer_cell_killing_death_rate",
        "description": "Uninfected Cancer Cell Killing Death Rate. Sets bundled SBML parameter `d_1`."
      },
      {
        "name": "infected_cancer_cell_killing_death_rate",
        "label": "Infected Cancer Cell Killing Death Rate",
        "units": "native source value",
        "default": 0.48,
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.infected_cancer_cell_killing_death_rate",
        "description": "Infected Cancer Cell Killing Death Rate. Sets bundled SBML parameter `c`."
      },
      {
        "name": "virus_release_rate",
        "label": "Virus Release Rate",
        "units": "native source value",
        "default": 2,
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.virus_release_rate",
        "description": "Virus Release Rate. Sets bundled SBML parameter `b`."
      }
    ],
    "outputs": [
      {
        "name": "uninfected_cancer_cells",
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.uninfected_cancer_cells"
      },
      {
        "name": "infected_cancer_cells",
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.infected_cancer_cells"
      },
      {
        "name": "free_virus",
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.free_virus"
      },
      {
        "name": "immune_cells",
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.immune_cells"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.species_labels"
      }
    ]
  },
  "title": "Al-Tuwairqi2020 - Dynamics of cancer virotherapy with immune response Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model",
      "alias": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model_state"
      ],
      "from": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model_summary"
      ],
      "from": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model_species_labels"
      ],
      "from": "immunology_sbml_al_tuwairqi2020_dynamics_of_cancer_virotherapy_w_biomd0000001035_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "This ordinary differential equation model of the role of the immune response in cancer virotherapy dynamics is described in the publication:Al-Tuwairqi, S.M., Al-Johani, N.O., Simbawa, E.A. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}