About lab
The model provides a framework for understanding rest/activity patterns effected by the circadian rhythm and relating them to underlying diverse phenotypes. It can be used to explore systemsbiology phillips2013 physiologically based modeling expl dynamics and compare simulation behavior across conditions.
Runtime
Duration1
Comms Step0.1
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Metadata
Packagephillips2013-physiologically-based-modeling-explaining-mammalian
Created2026-05-17
Updated2026-05-17
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation
Manifest
{
"io": {
"inputs": [
{
"name": "initial_h_sleep_homeostatic_drive",
"label": "Initial H Sleep Homeostatic Drive",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.initial_h_sleep_homeostatic_drive",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `H`."
},
{
"name": "initial_v_m_mean_cell_body_potential_ma",
"label": "Initial V M Mean Cell Body Potential Ma",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.initial_v_m_mean_cell_body_potential_ma",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `V_m`."
},
{
"name": "initial_v_v_mean_cell_body_potential_vlpo",
"label": "Initial V V Mean Cell Body Potential Vlpo",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.initial_v_v_mean_cell_body_potential_vlpo",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `V_v`."
},
{
"name": "initial_y_complement_of_x",
"label": "Initial Y Complement Of X",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.initial_y_complement_of_x",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Y`."
},
{
"name": "initial_x_scn_activity",
"label": "Initial X Scn Activity",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.initial_x_scn_activity",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `X`."
},
{
"name": "initial_n_fraction_of_photoreceptors_that_are_activated",
"label": "Initial N Fraction Of Photoreceptors That Are Activated",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.initial_n_fraction_of_photoreceptors_that_are_activated",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `n`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.species_labels"
},
{
"name": "h_sleep_homeostatic_drive",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.h_sleep_homeostatic_drive"
},
{
"name": "v_m_mean_cell_body_potential_ma",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.v_m_mean_cell_body_potential_ma"
},
{
"name": "v_v_mean_cell_body_potential_vlpo",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.v_v_mean_cell_body_potential_vlpo"
},
{
"name": "y_complement_of_x",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.y_complement_of_x"
},
{
"name": "x_scn_activity",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.x_scn_activity"
},
{
"name": "n_fraction_of_photoreceptors_that_are_activated",
"maps_to": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.n_fraction_of_photoreceptors_that_are_activated"
}
]
},
"tags": [
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Phillips2013 Physiologically Based Modeling Explaining Mammalian Rest A Lab",
"models": [
{
"path": "owned/models/systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model",
"alias": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model",
"provenance": {
"owned_path": "owned/models/systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model"
}
},
{
"path": "owned/models/visualisation",
"alias": "visualisation",
"provenance": {
"owned_path": "owned/models/visualisation"
}
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model_state"
],
"from": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model_summary"
],
"from": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model_species_labels"
],
"from": "systemsbiology_sbml_phillips2013_physiologically_based_modeling_expl_biomd0000001072_model.species_labels"
}
],
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"description": "The model provides a framework for understanding rest/activity patterns effected by the circadian rhythm and relating them to underlying diverse phenotypes. It can be used to explore systemsbiology phillips2013 physiologically based modeling expl dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
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