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Lai2007_O2_Transport_Metabolism Lab

About lab

This file describes the SBML version of the mathematical model in the following journal article: Linking Pulmonary Oxygen Uptake, Muscle Oxygen Utilization and Cellular Metabolism during Exercise, Ann. It can be used to explore metabolic flux dynamics and compare pathway behavior across conditions.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packagelai2007-o2-transport-metabolism-lab
Created2026-05-15
Updated2026-05-15
biomodels_ebifaithfulmetabolismodesbmltelluriumvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_atp",
        "units": "native SBML value",
        "default": 8.198857,
        "maps_to": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.initial_atp",
        "description": "Initial condition for atp. Maps to bundled SBML symbol `ATP`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_metabolic_pathway_state_2",
        "units": "native SBML value",
        "default": 40.98942,
        "maps_to": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.initial_metabolic_pathway_state_2",
        "description": "Initial condition for metabolic pathway state 2. Maps to bundled SBML symbol `PCr`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_adp",
        "units": "native SBML value",
        "default": 0.001142,
        "maps_to": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.initial_adp",
        "description": "Initial condition for adp. Maps to bundled SBML symbol `ADP`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_metabolic_pathway_state_4",
        "units": "native SBML value",
        "default": 1.01056,
        "maps_to": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.initial_metabolic_pathway_state_4",
        "description": "Initial condition for metabolic pathway state 4. Maps to bundled SBML symbol `Cr`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_metabolic_pathway_state_5",
        "units": "native SBML value",
        "default": 0.5,
        "maps_to": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.initial_metabolic_pathway_state_5",
        "description": "Initial condition for metabolic pathway state 5. Maps to bundled SBML symbol `Pi`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      }
    ],
    "outputs": [
      {
        "name": "atp",
        "maps_to": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.atp"
      },
      {
        "name": "metabolic_pathway_state_2",
        "maps_to": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.metabolic_pathway_state_2"
      },
      {
        "name": "adp",
        "maps_to": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.adp"
      },
      {
        "name": "metabolic_pathway_state_4",
        "maps_to": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.metabolic_pathway_state_4"
      },
      {
        "name": "metabolic_pathway_state_5",
        "maps_to": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.metabolic_pathway_state_5"
      },
      {
        "name": "observable_values",
        "maps_to": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.observable_values"
      },
      {
        "name": "run_summary",
        "maps_to": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.run_summary"
      },
      {
        "name": "observable_labels",
        "maps_to": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.observable_labels"
      }
    ]
  },
  "title": "Lai2007_O2_Transport_Metabolism Lab",
  "models": [
    {
      "path": "owned/models/metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model",
      "alias": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model",
      "parameters": {
        "model_path": "data/BIOMD0000000248.xml",
        "integration_step": 0.1
      },
      "provenance": {
        "owned_path": "owned/models/metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model_observable_values"
      ],
      "from": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.observable_values"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model_run_summary"
      ],
      "from": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.run_summary"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model_observable_labels"
      ],
      "from": "metabolism_sbml_lai2007_o2_transport_metabolism_biomd0000000248_model.observable_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "This file describes the SBML version of the mathematical model in the following journal article: Linking Pulmonary Oxygen Uptake, Muscle Oxygen Utilization and Cellular Metabolism during Exercise, Ann. It can be used to explore metabolic flux dynamics and compare pathway behavior across conditions.",
  "schema_version": "2.0"
}

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