Anderson2015 - Qualitative behavior of systems of tumor-CD4+-cytokine interactions with treatments Lab
About lab
This is a mathematical model describing tumor-CD4+-cytokine interactions, with specific emphasis on the role that CD4+ T lymphocytes play in tumor regression. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.
Runtime
Duration10
Comms Step1
Runs
Total0
Completed0
Failed0
Metadata
Packageanderson2015-qualitative-behavior-of-systems-of-tumor-cd4-cytoki
Created2026-05-15
Updated2026-05-15
immunologysbmlbiomodels_ebifaithfulcuratedvisualisation
Manifest
{
"io": {
"inputs": [
{
"name": "initial_tumor_cells",
"label": "Initial Tumor Cells",
"units": "native source value",
"default": 0.5,
"maps_to": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model.initial_tumor_cells",
"description": "Initial Tumor Cells. Sets the initial value of bundled SBML species `x_Tumor_Cells`."
},
{
"name": "initial_cd4_t_cells",
"label": "Initial CD4 T Cells",
"units": "native source value",
"default": 0.01,
"maps_to": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model.initial_cd4_t_cells",
"description": "Initial CD4 T Cells. Sets the initial value of bundled SBML species `y_CD4_T_Cells`."
},
{
"name": "initial_cytokine",
"label": "Initial Cytokine",
"units": "native source value",
"default": 0,
"maps_to": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model.initial_cytokine",
"description": "Initial Cytokine. Sets the initial value of bundled SBML species `z_Cytokine`."
},
{
"name": "tumor_growth_rate",
"label": "Tumor Growth Rate",
"units": "native source value",
"default": 0.03,
"maps_to": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model.tumor_growth_rate",
"description": "Tumor Growth Rate. Sets bundled SBML parameter `r`."
},
{
"name": "tumor_killing_rate",
"label": "Tumor Killing Rate",
"units": "native source value",
"default": 0.1,
"maps_to": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model.tumor_killing_rate",
"description": "Tumor Killing Rate. Sets bundled SBML parameter `delta`."
}
],
"outputs": [
{
"name": "tumor_cells",
"maps_to": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model.tumor_cells"
},
{
"name": "cd4_t_cells",
"maps_to": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model.cd4_t_cells"
},
{
"name": "cytokine",
"maps_to": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model.cytokine"
},
{
"name": "state",
"maps_to": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model.species_labels"
}
]
},
"title": "Anderson2015 - Qualitative behavior of systems of tumor-CD4+-cytokine interactions with treatments Lab",
"models": [
{
"path": "owned/models/immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model",
"alias": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model",
"provenance": {
"owned_path": "owned/models/immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model"
}
},
{
"path": "owned/models/visualisation",
"alias": "visualisation",
"provenance": {
"owned_path": "owned/models/visualisation"
}
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model_state"
],
"from": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model.state"
},
{
"to": [
"visualisation.immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model_summary"
],
"from": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model_species_labels"
],
"from": "immunology_sbml_anderson2015_qualitative_behavior_of_systems_of_biomd0000000813_model.species_labels"
}
],
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"description": "This is a mathematical model describing tumor-CD4+-cytokine interactions, with specific emphasis on the role that CD4+ T lymphocytes play in tumor regression. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
"schema_version": "2.0"
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