About lab
Source-faithful physiology lab for A model for pacemaking in substantia nigra neurons (A simple model based on a spherical geometry). Public controls and outputs are mapped to real source symbols for calcium handling.
Runtime
Duration0.01
Comms Step0.01
Settle Steps1
Runs
Total0
Completed0
Failed0
Metadata
Packagephysiome-3e0-pacemaking-substantia-nigra-neurons-simple-based-sp
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother
Manifest
{
"io": {
"inputs": [
{
"name": "initial_model_state_y_xm",
"label": "Initial Model State Y Xm (source y_xm)",
"maps_to": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.initial_model_state_y_xm",
"description": "Initial value for Model State Y Xm (source y_xm). Maps to source symbol `y_xm`. Units: dimensionless. Naming evidence: source symbol is dimensionless but lacks enough evidence for a biological label.",
"accepted_units": [
"dimensionless"
]
},
{
"name": "initial_intracellular_sodium",
"label": "Initial Intracellular Sodium",
"maps_to": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.initial_intracellular_sodium",
"description": "Initial value for Intracellular Sodium. Maps to source symbol `Na_i`. Units: mM. Naming evidence: source symbol, component, or units provide a direct public name.",
"accepted_units": [
"mM"
]
}
],
"outputs": [
{
"name": "state",
"label": "Selected Source State",
"maps_to": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.state"
},
{
"name": "summary",
"label": "Simulation Summary",
"maps_to": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.summary"
},
{
"name": "trajectory",
"label": "Source Trajectory",
"maps_to": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.trajectory"
},
{
"name": "variable_labels",
"label": "Observable Labels",
"maps_to": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.variable_labels"
},
{
"name": "membrane_voltage",
"label": "Membrane Voltage",
"maps_to": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.membrane_voltage",
"description": "Membrane Voltage. Maps to source symbol `V`. Units: mV. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "sodium_current",
"label": "Sodium Current",
"maps_to": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.sodium_current",
"description": "Sodium Current. Maps to source symbol `I_NaHCN`. Units: pA. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "sodium_current_i_na",
"label": "Sodium Current I Na",
"maps_to": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.sodium_current_i_na",
"description": "Sodium Current I Na. Maps to source symbol `I_Na`. Units: pA. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "sodium_current_i_nalk",
"label": "Sodium Current I Nalk",
"maps_to": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.sodium_current_i_nalk",
"description": "Sodium Current I Nalk. Maps to source symbol `I_Nalk`. Units: pA. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "sodium_current_i_nk",
"label": "Sodium Current I Nk",
"maps_to": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.sodium_current_i_nk",
"description": "Sodium Current I Nk. Maps to source symbol `I_nk`. Units: pA. Naming evidence: source symbol, component, or units provide a direct public name."
},
{
"name": "alpha_xm",
"label": "Alpha Xm",
"maps_to": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.alpha_xm",
"description": "Alpha Xm. Maps to source symbol `alpha_xm`. Units: per_ms. Naming evidence: source symbol, component, or units provide a direct public name."
}
]
},
"title": "Physiome 3e0 - Pacemaking Substantia Nigra Neurons Simple Based Spherical Lab",
"models": [
{
"path": "owned/models/physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model",
"alias": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model",
"parameters": {
"model_path": "data/francis_garcia_middleton_2012_spherical.cellml",
"integration_step": 0.01
},
"provenance": {
"owned_path": "owned/models/physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model"
}
},
{
"path": "owned/models/visualisation",
"alias": "visualisation",
"provenance": {
"owned_path": "owned/models/visualisation"
}
}
],
"wiring": [
{
"to": [
"visualisation.physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model_state"
],
"from": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.state"
},
{
"to": [
"visualisation.physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model_summary"
],
"from": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.summary"
},
{
"to": [
"visualisation.physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model_trajectory"
],
"from": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.trajectory"
},
{
"to": [
"visualisation.physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model_variable_labels"
],
"from": "physiology_cellml_a_model_for_pacemaking_in_substantia_nigra_neuro_3e0_model.variable_labels"
}
],
"runtime": {
"duration": 0.01,
"settle_steps": 1,
"initial_inputs": {},
"communication_step": 0.01
},
"description": "Source-faithful physiology lab for A model for pacemaking in substantia nigra neurons (A simple model based on a spherical geometry). Public controls and outputs are mapped to real source symbols for calcium handling.",
"schema_version": "2.0"
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