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Hayer2005 Simple Ampar Traff Lab

About lab

This is a highly simplified model of the AMPAR trafficking cycle that exhibits bistability. It can be used to explore systemsbiology hayer2005 simple ampar traff model2 dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packagehayer2005-simple-ampar-traff-lab
Created2026-05-17
Updated2026-05-17
signalingsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_internal_slash_ir_star",
        "label": "Initial Internal Slash Ir Star",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.initial_internal_slash_ir_star",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Internal_slash_IR_star_`."
      },
      {
        "name": "initial_internal_slash_ir",
        "label": "Initial Internal Slash Ir",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.initial_internal_slash_ir",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Internal_slash_IR`."
      },
      {
        "name": "initial_pka_minus_active_slash_internal_minus_pka_minus_act_slash_internal_minus_pka_minus_act_cplx",
        "label": "Initial Pka Minus Active Slash Internal Minus Pka Minus Act Slash Internal Minus Pka Minus Act Cplx",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.initial_pka_minus_active_slash_internal_minus_pka_minus_act_slash_internal_minus_pka_minus_act_cplx",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `PKA_minus_active_slash_internal_minus_PKA_minus_act_slash_internal_minus_PKA_minus_act_cplx`."
      },
      {
        "name": "initial_pka_minus_active_slash_internal_minus_pka_minus_act_sbo_1_sbc_slash_internal_minus_pka_minus_act_sbo_1_sbc_cplx",
        "label": "Initial Pka Minus Active Slash Internal Minus Pka Minus Act Sbo 1 Sbc Slash Internal Minus Pka Minus Act Sbo 1 Sbc Cplx",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.initial_pka_minus_active_slash_internal_minus_pka_minus_act_sbo_1_sbc_slash_internal_minus_pka_minus_act_sbo_1_sbc_cplx",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `PKA_minus_active_slash_internal_minus_PKA_minus_act_sbo_1_sbc__slash_internal_minus_PKA_minus_act_sbo_1_sbc__cplx`."
      },
      {
        "name": "initial_internal_slash_ir_star_star",
        "label": "Initial Internal Slash Ir Star Star",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.initial_internal_slash_ir_star_star",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Internal_slash_IR_star__star_`."
      },
      {
        "name": "initial_anchor",
        "label": "Initial Anchor",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.initial_anchor",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Anchor`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.species_labels"
      },
      {
        "name": "internal_slash_ir_star",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.internal_slash_ir_star"
      },
      {
        "name": "internal_slash_ir",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.internal_slash_ir"
      },
      {
        "name": "pka_minus_active_slash_internal_minus_pka_minus_act_slash_internal_minus_pka_minus_act_cplx",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.pka_minus_active_slash_internal_minus_pka_minus_act_slash_internal_minus_pka_minus_act_cplx"
      },
      {
        "name": "pka_minus_active_slash_internal_minus_pka_minus_act_sbo_1_sbc_slash_internal_minus_pka_minus_act_sbo_1_sbc_cplx",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.pka_minus_active_slash_internal_minus_pka_minus_act_sbo_1_sbc_slash_internal_minus_pka_minus_act_sbo_1_sbc_cplx"
      },
      {
        "name": "internal_slash_ir_star_star",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.internal_slash_ir_star_star"
      },
      {
        "name": "anchor",
        "maps_to": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.anchor"
      }
    ]
  },
  "tags": [
    "signaling",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Hayer2005 Simple Ampar Traff Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model",
      "alias": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model_state"
      ],
      "from": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model_summary"
      ],
      "from": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model_species_labels"
      ],
      "from": "systemsbiology_sbml_hayer2005_simple_ampar_traff_model2_model9086628127_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "This is a highly simplified model of the AMPAR trafficking cycle that exhibits bistability. It can be used to explore systemsbiology hayer2005 simple ampar traff model2 dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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