Maldonado2006 - Mathematical Predicts Critical Role Osteoclast Autocrine Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_bone_radius",
        "label": "Initial Bone Radius",
        "maps_to": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.initial_bone_radius",
        "description": "Initial value for Bone Radius. Maps to source symbol `r_B`. Units: mm. Naming evidence: source metadata names `r_B` as `bone radius`.",
        "accepted_units": [
          "mm"
        ]
      },
      {
        "name": "initial_nitric_oxide_concentration",
        "label": "Initial Nitric Oxide Concentration",
        "maps_to": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.initial_nitric_oxide_concentration",
        "description": "Initial value for Nitric Oxide Concentration. Maps to source symbol `x_no`. Units: pM. Naming evidence: source metadata names `x_no` as `nitric oxide concentration`.",
        "accepted_units": [
          "pM"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.variable_labels"
      },
      {
        "name": "bone_radius",
        "label": "Bone Radius",
        "maps_to": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.bone_radius",
        "description": "Bone Radius. Maps to source symbol `r_B`. Units: mm. Naming evidence: source metadata names `r_B` as `bone radius`."
      },
      {
        "name": "osteoblast_population",
        "label": "Osteoblast Population",
        "maps_to": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.osteoblast_population",
        "description": "Osteoblast Population. Maps to source symbol `xb`. Units: pM. Naming evidence: source metadata names `xb` as `osteoblast population`."
      },
      {
        "name": "osteoclast_population",
        "label": "Osteoclast Population",
        "maps_to": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.osteoclast_population",
        "description": "Osteoclast Population. Maps to source symbol `xc`. Units: pM. Naming evidence: source metadata names `xc` as `osteoclast population`."
      },
      {
        "name": "osteocyte_population",
        "label": "Osteocyte Population",
        "maps_to": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.osteocyte_population",
        "description": "Osteocyte Population. Maps to source symbol `xy`. Units: pM. Naming evidence: source metadata names `xy` as `osteocyte population`."
      },
      {
        "name": "rankl_concentration",
        "label": "Rankl Concentration",
        "maps_to": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.rankl_concentration",
        "description": "Rankl Concentration. Maps to source symbol `x_kl`. Units: pM. Naming evidence: source metadata names `x_kl` as `RANKL concentration`."
      },
      {
        "name": "responding_osteoblast_population",
        "label": "Responding Osteoblast Population",
        "maps_to": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.responding_osteoblast_population",
        "description": "Responding Osteoblast Population. Maps to source symbol `xr`. Units: pM. Naming evidence: source metadata names `xr` as `responding osteoblast population`."
      }
    ]
  },
  "title": "Maldonado2006 - Mathematical Predicts Critical Role Osteoclast Autocrine Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model",
      "alias": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model",
      "parameters": {
        "model_path": "data/maldonado_2006.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model_state"
      ],
      "from": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model_summary"
      ],
      "from": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model_trajectory"
      ],
      "from": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model_variable_labels"
      ],
      "from": "physiology_cellml_maldonado_borchers_findeisen_and_allgower_2006_maldonadoborchersfindeisenallgower2006_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Maldonado, Borchers, Findeisen and Allgower, 2006. Public controls and outputs are mapped to real source symbols for bone and endocrine physiology.",
  "schema_version": "2.0"
}