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Proctor2017 Role Of Micrornas In Osteoarthritis 2 Lab

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Proctor2017- Role of microRNAs inosteoarthritis (Negative Feedback By MicroRNA with Delay) This model is described in the article: Computer simulation models as a tool to investigate the role of micro. It can be used to explore systemsbiology proctor2017 role of micrornas in dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
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Metadata

Packageproctor2017-role-of-micrornas-in-osteoarthritis-2-lab
Created2026-05-17
Updated2026-05-17
generegulationsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_signal",
        "label": "Initial Signal",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.initial_signal",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Signal`."
      },
      {
        "name": "initial_mi_r_gene",
        "label": "Initial Mi R Gene",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.initial_mi_r_gene",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `miR_gene`."
      },
      {
        "name": "initial_tf1_nuc",
        "label": "Initial TF1 Nuc",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.initial_tf1_nuc",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `TF1_nuc`."
      },
      {
        "name": "initial_tf1_mrna",
        "label": "Initial TF1 MRNA",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.initial_tf1_mrna",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `TF1_mRNA`."
      },
      {
        "name": "initial_tf1_cyt",
        "label": "Initial TF1 Cyt",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.initial_tf1_cyt",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `TF1_cyt`."
      },
      {
        "name": "initial_sink",
        "label": "Initial Sink",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.initial_sink",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Sink`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.species_labels"
      },
      {
        "name": "signal",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.signal"
      },
      {
        "name": "mi_r_gene",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.mi_r_gene"
      },
      {
        "name": "tf1_nuc",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.tf1_nuc"
      },
      {
        "name": "tf1_mrna",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.tf1_mrna"
      },
      {
        "name": "tf1_cyt",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.tf1_cyt"
      },
      {
        "name": "sink",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.sink"
      }
    ]
  },
  "tags": [
    "generegulation",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Proctor2017 Role Of Micrornas In Osteoarthritis 2 Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model",
      "alias": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model_state"
      ],
      "from": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model_summary"
      ],
      "from": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model_species_labels"
      ],
      "from": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1610100002_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Proctor2017- Role of microRNAs inosteoarthritis (Negative Feedback By MicroRNA with Delay) This model is described in the article: Computer simulation models as a tool to investigate the role of micro. It can be used to explore systemsbiology proctor2017 role of micrornas in dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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