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Zager2007 Genistein Biliary Excretion Lab

About lab

This the model from the article without the time delays: A Delayed Nonlinear PBPK Model for Genistein Dosimetry in Rats. It can be used to explore systemsbiology zager2007 genistein biliary excretion model6963432821 dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packagezager2007-genistein-biliary-excretion-lab
Created2026-05-17
Updated2026-05-17
pharmacologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_cgen_rp",
        "label": "Initial Cgen Rp",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.initial_cgen_rp",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Cgen_rp`."
      },
      {
        "name": "initial_cgen_pp",
        "label": "Initial Cgen Pp",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.initial_cgen_pp",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Cgen_pp`."
      },
      {
        "name": "initial_cgen_l",
        "label": "Initial Cgen L",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.initial_cgen_l",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Cgen_l`."
      },
      {
        "name": "initial_cgen_gi",
        "label": "Initial Cgen Gi",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.initial_cgen_gi",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Cgen_GI`."
      },
      {
        "name": "initial_ccon_rob",
        "label": "Initial Ccon Rob",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.initial_ccon_rob",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ccon_ROB`."
      },
      {
        "name": "initial_ccon_l",
        "label": "Initial Ccon L",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.initial_ccon_l",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ccon_l`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.species_labels"
      },
      {
        "name": "cgen_rp",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.cgen_rp"
      },
      {
        "name": "cgen_pp",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.cgen_pp"
      },
      {
        "name": "cgen_l",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.cgen_l"
      },
      {
        "name": "cgen_gi",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.cgen_gi"
      },
      {
        "name": "ccon_rob",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.ccon_rob"
      },
      {
        "name": "ccon_l",
        "maps_to": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.ccon_l"
      }
    ]
  },
  "tags": [
    "pharmacology",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Zager2007 Genistein Biliary Excretion Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model",
      "alias": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model_state"
      ],
      "from": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model_summary"
      ],
      "from": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model_species_labels"
      ],
      "from": "systemsbiology_sbml_zager2007_genistein_biliary_excretion_model6963432821_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "This the model from the article without the time delays: A Delayed Nonlinear PBPK Model for Genistein Dosimetry in Rats. It can be used to explore systemsbiology zager2007 genistein biliary excretion model6963432821 dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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