Leander2021 - innate immune response to SARS-CoV-2 in the alveolar epithelium Lab

{
  "io": {
    "inputs": [
      {
        "name": "viral_infection_rate",
        "label": "Viral Infection Rate",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.viral_infection_rate"
      },
      {
        "name": "virus_clearance_rate",
        "label": "Virus Clearance Rate",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.virus_clearance_rate"
      },
      {
        "name": "viral_production_rate",
        "label": "Viral Production Rate",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.viral_production_rate"
      },
      {
        "name": "macrophage_activation_rate",
        "label": "Macrophage Activation Rate",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.macrophage_activation_rate"
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Model state",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Species labels",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.species_labels"
      },
      {
        "name": "viral_load",
        "label": "Viral load",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.viral_load"
      },
      {
        "name": "alveolar_type_1_cells",
        "label": "Alveolar type I cells",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.alveolar_type_1_cells"
      },
      {
        "name": "ace2_positive_type_2_cells",
        "label": "ACE2-positive type II alveolar cells",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.ace2_positive_type_2_cells"
      },
      {
        "name": "activated_ace2_positive_type_2_cells",
        "label": "Activated ACE2-positive type II alveolar cells",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.activated_ace2_positive_type_2_cells"
      },
      {
        "name": "infected_cells",
        "label": "Infected cells",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.infected_cells"
      },
      {
        "name": "activated_macrophages",
        "label": "Activated macrophages",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.activated_macrophages"
      },
      {
        "name": "interferon_signal",
        "label": "Interferon signal",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.interferon_signal"
      },
      {
        "name": "t_cell_response",
        "label": "T cell response",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.t_cell_response"
      },
      {
        "name": "damaged_cells",
        "label": "Damaged cells",
        "maps_to": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.damaged_cells"
      }
    ]
  },
  "title": "Leander2021 - innate immune response to SARS-CoV-2 in the alveolar epithelium Lab",
  "models": [
    {
      "path": "owned/models/epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model",
      "alias": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model",
      "parameters": {
        "model_path": "data/MODEL2111170001.xml",
        "integration_step": "1e-6"
      },
      "provenance": {
        "owned_path": "owned/models/epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model_state"
      ],
      "from": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.state"
    },
    {
      "to": [
        "visualisation.epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model_summary"
      ],
      "from": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.summary"
    },
    {
      "to": [
        "visualisation.epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model_species_labels"
      ],
      "from": "epidemiology_sbml_leander2021_innate_immune_response_to_sars_cov_2_model2111170001_model.species_labels"
    }
  ],
  "runtime": {
    "duration": "1e-6",
    "initial_inputs": {},
    "communication_step": "1e-6"
  },
  "description": "Single-model lab wrapper for Leander2021 - innate immune response to SARS-CoV-2 in the alveolar epithelium. A mathematical ODE based model of the innate immune response to SARS-CoV-2 in the alveolar epithelium. It can be used to explore transmission dynamics and compare scenario outcomes across conditions.",
  "schema_version": "2.0"
}